Predictive, Preventive & Personalized Medicine and Molecular Diagnostics

Proteomics and Genomics in Personalized Medicine

The proteome is the entire set of proteins it is expressed by genome , cell, tissue, or organism at a certain time. More specifically, it is a combined of proteins and genomes . Proteomics is the study of the proteome. A cellular  proteome is the collection of proteins present in a particular cell type and it exposure to harmone stimulation . It can also be useful to consider an organisms complete proteome, which can be conceptualized as the complete set of proteins from all of the various cellular proteomes. Proteome used to refer to the collection of proteins in certain sub-cellular biological systems .

Pharmacogenomics is the study of  the role of genetics in drug response. It deals with the influence of acquired and inherited genetic variation on drug response, drug absorption distribution, metabolism, and elimination ,as well as drug receptor target effects . Pharmacogenomics isoften used interchangeably with pharmacogenetics. Pharmacogenomics is used for the detection of   the individual genetic variation with drug responses pharmacogenetics focuses on single drug-gene interactions, incorporating genomics and epigenetics while dealing with the effects of multiple genes on drug response.