Pharmacogenetics in Personalized Medicine
In personalized medicine pharmacogenetics is the study of inherited genetic differences in drug metabolic pathways which can affect the drug responses, like therapeutic effect as well as adverse effect. Inter- and intra-individual variation in gene expression and its function.In oncology, pharmacogenetics refers to germline mutations and pharmacogenomics is study the somatic mutations in tumoral DNA leading to alteration in drug response.
- Pharmacogenetics and drug development
- Drugs metabolized by CYP2C19
- Careers in pharmacogenomics
- Pharmacogenetics and adverse drug reactions
- Next Generation Sequencing
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