7^th International Conference on Predictive, Preventive and Personalized Medicine & Molecular Diagnostics Oct 05-06, 2017 Chicago, Illinois, USA

Aim: Evaluation of red cell transfusion effects on tissue oxygenation, by measuring blood lactate levels before and after hemotransfusion.Blood lactate level are suggested as sesitive parameter to evaluete tissue oxigenation.The aim of this stydy was to verify the efficiency of hemotransfusions that were performed on patients in intensiv care based on lactate level.\r\nMaterial and Methods: In this prospective observational stydy on(n- 59 patients) who considered that required red cell transfusion .(the patients more that 25 point according to APACHE II-score were excluded).We monitor vital sings(BP,HR,Age,APACHE II-- score) at addmision time, and also was stictly observed lactate level and hemoglobin level at addmision before red cell transfusion (pre T), two hours after transfusion (2h post T) and 24 hours after (24 h post T with or no any another red cell transfusion).At first the patients group based at hemoglobin level, Group Ia with Hb< 8g/dl and Group IIb with Hb ≥ 8g/dl. After that the patients group again based at lactate level,Group Ic lactat level ≥ 2,4 and Group IId lactate level <2,4.\r\nResults: Among another findings,comparison between group Ic and group IId showed that patients belong at group Ic needed 3 more time blood packs that patients on group IId with statistical significance (p < 0.01).On the other hand ,we concluded statistical differences (p < 0.05) between groups Ic and IId on admission time as belongs vital parameters , such as blood presure, heart rate,age and APACHE II- score. \r\n Conclusions: Statistical significance evaluation (p < 0,05) between above mentioned groups shown that lactate level and vital parameters are sensitive indicators in evaluation of blood needs for patients on ICU. \r\n Key words : red cell transfusion,lactat level, hemoglobin level,oxygenation,anemia.\r\n