Timothy Yap
UK
Biography
Technological advancements in the molecular characterization of cancers have enabled researchers to identify an increasing number of key molecular drivers of cancer progression. These discoveries have led to multiple novel anticancer therapeutics, and clinical benefit in selected patient populations. Despite this, the identification of clinically relevant predictive biomarkers of response continues to lag behind. In this presentation, strategies for the molecular characterization of cancers and the importance of biomarkers for the development of novel antitumor therapeutics are discussed. We also review critical successes and failures in oncology, as well as the lessons learnt, which may aid in the acceleration of anticancer drug development and biomarker discovery are reviewed.
Abstract
Abstract : Strategies for modern biomarker and drug development in the era of personalized cancer medicine