Constantin Polychronakos
The Research Institute of the McGill Health Centre, Canada
Biography
Constantin Polychronakos studied Medicine at the Aristotelian University in Greece, following which he moved to Canada and trained in Pediatric Endocrinology,rnfollowed by a research fellowship at the Polypeptide Hormone Laboratory at McGill University in Montreal. Since 1983 he is on faculty at McGill Universityrn(Full Professor since 2000). For the past three decades, his research is focused on the genetics and immunology of diabetes. He has played a central rolern(corresponding author) in the fi rst GWAS for type 2 and one of the fi rst two for type-1 diabetes. He has also done seminal work on the role of thymus in the immunernself-tolerance to tissue-specifi c antigens like insulin and in one of the fi rst uses of exon capture+NGS, he discovered RFX6 as the gene whose mutations abrogaternthe development of the endocrine pancreas
Abstract
Abstract : Personalised medicine in autoimmune disease: Type 1 diabetes as a paradigm