Kamalidin Sharipov
Asfendiyarov Kazakh National Medical University, Kazakhstan
Title: The role of omiks technology in the formation of personalized medicine and research of metallom
Biography
Biography: Kamalidin Sharipov
Abstract
Medicine of the XXI century is inseparably linked and more often uses data of omiks technologies for the diagnosis and treatment of different diseases. The using of myltuomics technology in biomedicine contributes to the formation of innovative concept of individual approach to each patient, i.e. personalized medicine. In the development of personalized medicine not only use genomic technologies and genotyping, but other omiks technologies such as metabolome research, methabonome, metallom, etc. Metallom – is a quantitative measurement of metallom components (products of interaction of ionic and atomic forms of metals with endogenous ligands) Nowadays the role of many chemical elements is established in processes of growth, differentiation, regeneration, cell apoptosis and necrosis, as well as in the pathogenesis of some diseases, which is accompanied by significant changes in the element status of body. In our research’s we determined the content of metallom component more than 25 chemical elements including vitally important in people's hair and improved personalized approach to each patient based on identified regularities of quantitative changes in the body. As would be expected elementogramma of examinees people were mostly in the normal range, and some deviations had multidirectional nature. Deviation of essential and trace elements from norm was more specific (for such elements as cobalt, zinc and copper downward and for silicon upward, that might indicate or lead to in the future to certain orphan diseases or disturbing signal comprehensive study and personalized approach).Thus, we can conclude, that a personalized approach to increase the effectiveness of treatment for each patient with using myltuomics technology and provides specific therapeutic effects, reducing the risk of unwanted side effects, precludes mistake assignment ineffective drugs reduces the cost of treatment and develops predictive and preventive medicine.