Mohamed Abdulla
Primary care center, Sweden
Title: Diet, microbiome, health and social well-being - Personalized Medicine
Biography
Biography: Mohamed Abdulla
Abstract
The relationship between the body and diet is a very intimate one compared to all other relations. During the 1960s and 1970s, dietary manipulations, especially caloric restrictions were found to retard aging. Research during the last couple of decades has shown that the number of independent molecules-processors contribute to human aging. Th is includes Metformin, Ratamycin, Resveratroan, Free radicals, hormones and gene modifi cations. Ratamycin and related compounds such as Everolimus and Temsirolimus are found to interfere with the activity of a protein called Mammalian Tor (mTor). All these compounds and processors are known to extend the lifespan of a number of experimental animals and postpone age-related disorders such as cardio vascular diseases and cancer. Metformin is a very commonly used drug against diabetes and recent studies in England have shown that it can prolong the lifespan of humans without having diabetes. Free radicals theory of aging has become less specifi c in animals as well as in humans during the last decade. Th ere are a number of genes that are known to interfere with human aging. Manipulation of some of these genes has found to increase human lifespan in some selected areas of the world. Telommeres are the time keepers of a self-life; each time a cell divides the length of the Telommeres is shortened and fi nally it disappears altogether. Many researchers are active at present in order to fi nd ways of keeping Telommeres intact. In young blood cells there is a protein (GD lever) that is abunded one is young and giving the blood from younger mice to older ones to increase the lifespan of the older mice. Th is paper will describe some of the details of the molecule processors involved in the aging process. It will also discuss the importance of microbiome that infl uences health and disease