William G Kearns
President and Director of AdvaGenix, USA
Title: Personalized Genomics within Reproductive Medicine
Biography
Biography: William G Kearns
Abstract
With the rapid pace of progress in the fields of biotechnology, genetics, and genomics, molecular genetic profiling may soon become an integral tool for clinicians to guide individualized management of many medical conditions. Personalized medicine (also termed personalized genomics, genomic medicine, or precision medicine) refers to the application of patient-specific profiles, incorporating genetic and genomic data as well as clinical and environmental factors, to assess individual risks and tailor prevention and disease-management strategies. Personalized medicine involves the use of an individual's genetic profile to guide decisions made in regards to the prevention, diagnosis, and treatment of disease. The definition encompasses a broad range of current clinical practices in which genomic results are used to guide patient care. We will discuss the applications of whole exome sequencing and reproductive medicine based upon a family profile for genetic diseases that are lethal or with high morbidity. Trio data will be presented and discussed regarding the use and application of personalized medicine in respect to a family’s desire to have healthy children.